5 Easy Facts About LDN-27219 side effects Described
One especially fascinating compound is LDN-27219. While most tTG inhibitors are designed to bind into the protein crosslinking Energetic web-site, LDN-27219 as a substitute binds on the nucleotide binding pocket in the enzyme while it is in its closed-point out conformation, and stabilizes that conformation to forestall crosslinking activity.78 Sch